hrp0097p2-3 | Adrenals and HPA Axis | ESPE2023

Glucocorticoid induced adrenal insufficiency evaluated by the low dose short corticotropin test in children

Nauwynck Elise , Knauf Keanu , Anckaert Ellen , Vanbesien Jesse , Staels Willem , De Schepper Jean , Gies Inge

Background and aims: The low dose short corticotropin test (LCT) is the most frequently used test to diagnose glucocorticoid-induced adrenal insufficiency (GAI) in children. Result of the LCT must be interpreted with caution since stimulated peak cortisol (PC) thresholds depend on the assay and time of sampling. We evaluated the prevalence of GAI by the LCT using both 20 and 30 minutes sampling and cortisol measurements by the most recent Roche Elecsys Cortiso...

hrp0095p1-473 | Fat, Metabolism and Obesity | ESPE2022

Prevalence and determinants of hyperuricemia in a Belgian multi-ethnic inner-city population of overweight/obese children and adolescents

Nauwynck Elise , Vanbesien Jesse , Staels Willem , Ryckx Sofie , Verheyden Stefanie , Rutteman Bart , Weets Ilse , De Schepper Jean , Gies Inge

Background/ Aims: Hyperuricemia (HU) is a frequent finding in childhood obesity, ranging between 12 and 40%, and associates to a variable extent with different components of the metabolic syndrome (MS). In this study, the effect of gender, (a Belgian native vs a non-Belgian native) descent and degree of general and central adiposity on serum uric acid (SUA) and the prevalence of HU was investigated in a multi-ethnic population of overweight/obese children and ...